Influence of fitness and age on the endothelial response to acute inflammation.
Identifieur interne : 000996 ( Main/Exploration ); précédent : 000995; suivant : 000997Influence of fitness and age on the endothelial response to acute inflammation.
Auteurs : Elizabeth C. Schroeder [États-Unis] ; Abbi D. Lane-Cordova [États-Unis] ; Sushant M. Ranadive [États-Unis] ; Tracy Baynard [États-Unis] ; Bo Fernhall [États-Unis]Source :
- Experimental physiology [ 1469-445X ] ; 2018.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Aptitude physique (physiologie), Capacité cardiorespiratoire (physiologie), Consommation d'oxygène (physiologie), Endothélium vasculaire (métabolisme), Endothélium vasculaire (physiopathologie), Exercice physique (physiologie), Femelle, Humains, Inflammation (métabolisme), Inflammation (physiopathologie), Jeune adulte, Marqueurs biologiques (métabolisme), Mâle, Pression artérielle (physiologie), Rigidité vasculaire (physiologie), Sujet âgé, Vieillissement (métabolisme), Vieillissement (physiologie).
- MESH :
- métabolisme : Endothélium vasculaire, Inflammation, Marqueurs biologiques, Vieillissement.
- physiologie : Aptitude physique, Capacité cardiorespiratoire, Consommation d'oxygène, Exercice physique, Pression artérielle, Rigidité vasculaire, Vieillissement.
- physiopathologie : Endothélium vasculaire, Inflammation.
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Humains, Jeune adulte, Mâle, Sujet âgé.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aging (metabolism), Aging (physiology), Arterial Pressure (physiology), Biomarkers (metabolism), Cardiorespiratory Fitness (physiology), Endothelium, Vascular (metabolism), Endothelium, Vascular (physiopathology), Exercise (physiology), Female, Humans, Inflammation (metabolism), Inflammation (physiopathology), Male, Middle Aged, Oxygen Consumption (physiology), Physical Fitness (physiology), Vascular Stiffness (physiology), Young Adult.
- MESH :
- chemical , metabolism : Biomarkers.
- metabolism : Aging, Endothelium, Vascular, Inflammation.
- physiology : Aging, Arterial Pressure, Cardiorespiratory Fitness, Exercise, Oxygen Consumption, Physical Fitness, Vascular Stiffness.
- physiopathology : Endothelium, Vascular, Inflammation.
- Adolescent, Adult, Aged, Female, Humans, Male, Middle Aged, Young Adult.
Abstract
What is the central question of the study? What are the effects of age and fitness on the vascular response to acute inflammation in younger and older adults? What is the main finding and its importance? In older adults, cardiorespiratory fitness level has a differential impact on endothelial function after acute inflammation. Compared with older adults with low fitness, older, moderately fit adults have a greater decrease in endothelial function, similar to that of younger adults. These findings have important implications in support of the beneficial effects of higher cardiorespiratory fitness in maintaining vascular reactivity and the ability to respond to stressors.
DOI: 10.1113/EP086922
PubMed: 29659080
Affiliations:
- États-Unis
- Caroline du Sud, Illinois, Maryland
- Chicago, College Park (Maryland)
- Université de l'Illinois à Chicago, Université du Maryland
Links toward previous steps (curation, corpus...)
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Le document en format XML
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<term>Aging (metabolism)</term>
<term>Aging (physiology)</term>
<term>Arterial Pressure (physiology)</term>
<term>Biomarkers (metabolism)</term>
<term>Cardiorespiratory Fitness (physiology)</term>
<term>Endothelium, Vascular (metabolism)</term>
<term>Endothelium, Vascular (physiopathology)</term>
<term>Exercise (physiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Inflammation (metabolism)</term>
<term>Inflammation (physiopathology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Oxygen Consumption (physiology)</term>
<term>Physical Fitness (physiology)</term>
<term>Vascular Stiffness (physiology)</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aptitude physique (physiologie)</term>
<term>Capacité cardiorespiratoire (physiologie)</term>
<term>Consommation d'oxygène (physiologie)</term>
<term>Endothélium vasculaire (métabolisme)</term>
<term>Endothélium vasculaire (physiopathologie)</term>
<term>Exercice physique (physiologie)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Inflammation (métabolisme)</term>
<term>Inflammation (physiopathologie)</term>
<term>Jeune adulte</term>
<term>Marqueurs biologiques (métabolisme)</term>
<term>Mâle</term>
<term>Pression artérielle (physiologie)</term>
<term>Rigidité vasculaire (physiologie)</term>
<term>Sujet âgé</term>
<term>Vieillissement (métabolisme)</term>
<term>Vieillissement (physiologie)</term>
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<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Aging</term>
<term>Endothelium, Vascular</term>
<term>Inflammation</term>
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<term>Marqueurs biologiques</term>
<term>Vieillissement</term>
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<term>Capacité cardiorespiratoire</term>
<term>Consommation d'oxygène</term>
<term>Exercice physique</term>
<term>Pression artérielle</term>
<term>Rigidité vasculaire</term>
<term>Vieillissement</term>
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<term>Arterial Pressure</term>
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<term>Exercise</term>
<term>Oxygen Consumption</term>
<term>Physical Fitness</term>
<term>Vascular Stiffness</term>
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<term>Inflammation</term>
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<front><div type="abstract" xml:lang="en">What is the central question of the study? What are the effects of age and fitness on the vascular response to acute inflammation in younger and older adults? What is the main finding and its importance? In older adults, cardiorespiratory fitness level has a differential impact on endothelial function after acute inflammation. Compared with older adults with low fitness, older, moderately fit adults have a greater decrease in endothelial function, similar to that of younger adults. These findings have important implications in support of the beneficial effects of higher cardiorespiratory fitness in maintaining vascular reactivity and the ability to respond to stressors.</div>
</front>
</TEI>
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</country>
<region><li>Caroline du Sud</li>
<li>Illinois</li>
<li>Maryland</li>
</region>
<settlement><li>Chicago</li>
<li>College Park (Maryland)</li>
</settlement>
<orgName><li>Université de l'Illinois à Chicago</li>
<li>Université du Maryland</li>
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<tree><country name="États-Unis"><region name="Illinois"><name sortKey="Schroeder, Elizabeth C" sort="Schroeder, Elizabeth C" uniqKey="Schroeder E" first="Elizabeth C" last="Schroeder">Elizabeth C. Schroeder</name>
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<name sortKey="Baynard, Tracy" sort="Baynard, Tracy" uniqKey="Baynard T" first="Tracy" last="Baynard">Tracy Baynard</name>
<name sortKey="Fernhall, Bo" sort="Fernhall, Bo" uniqKey="Fernhall B" first="Bo" last="Fernhall">Bo Fernhall</name>
<name sortKey="Lane Cordova, Abbi D" sort="Lane Cordova, Abbi D" uniqKey="Lane Cordova A" first="Abbi D" last="Lane-Cordova">Abbi D. Lane-Cordova</name>
<name sortKey="Ranadive, Sushant M" sort="Ranadive, Sushant M" uniqKey="Ranadive S" first="Sushant M" last="Ranadive">Sushant M. Ranadive</name>
</country>
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